NBC’s newest sitcom, ‘Are You There Vodka? It’s Me Chelsea’, hasn’t aired yet but it already dropped three of its main cast members for “creative reasons”.

Jo Koy, who frequently appears in Chelsea Handler’s ‘Chelsea Lately’ roundtable segment, was supposed to play Chelsea’s bartender friend and co-worker who is a frequent victim of Chelsea’s pranks and verbal exploits. He has been “let go” from the show’s acting roster, along with former ‘ER’ star Angel Laketa Moore and ‘Parks and Recreation’ alum Natalie Morales. Moore plays another of Chelsea’s co-workers, a spunky waitress who sometimes doubles as the comedienne’s voice of reason. Morales on the other hand plays Ivory, Chelsea’s best friend who is as feisty and sassy as the comedienne herself.

TV Line broke the news of the show’s major casting changes. This actually comes a bit of a shocker since promotional machinery for the new series is already underway, with the three actors appearing in the videos and photos plugging the show. As of press time, NBC reps have not released a statement regarding the matter.

‘Are You There Vodka? It’s Me Chelsea’ is the TV adaptation of Chelsea Handler’s New York Times bestseller of the same name, which chronicles Handler’s early life in Los Angeles as a waitress and a budding comedienne. The series stars Laura Prepon of ‘That ‘70s Show’ fame as Handler, while the author and ‘Chelsea Lately’ host stars as her own sister, Sloane. The show is slated for a mid-season premiere.